Our custom RNA synthesis service offerings include siRNA and microRNA, as well as uniquely long and/or chemically modified RNAs.

Custom RNA

Create and order ssRNA oligos with a wide variety of chemical modifications

Custom siRNA

Create a custom siRNA specific for your application

Custom microRNA

Modify an existing microRNA mimic or inhibitor, target a novel microRNA, or request an Accell microRNA for special applications

Midscale oligo manufacturing

Quality custom oligonucleotides for research and preclinical applications

Custom synthesis brochure

Custom synthesis brochure

Custom RNA synthesis by Dharmacon™ offers experimental flexibility with limitless modifications, greater yields and faster delivery than any other synthesis service

Incorporating molecular probes at any RNA site

Incorporation of molecular probes at defined sites within synthetic RNA was accomplished using the 2’-ACE®-5’-Silyl RNA synthesis platform in combination with the Levulinyl protecting group. This process results in excellent yields of modified full length RNA and superior qualities. 

Interested in prime editing?

Horizon is the world leader in long oligo synthesis. Contact us to discuss your pegRNA or other long oligo needs.

TIDES Report - Long RNA synthesis

See how 2'-ACE chemistry allows Horizon to design long oligos at extremely high yields, with nearly limitless modification options!

Preclinical oligo synthesis

Get oligonucleotides to the clinic faster! Expedite the journey with a reliable, experienced supplier of research, preclinical, and OEM oligonucleotides.