Custom oligo synthesis
Flexible scale and purity to fit experimental needs and budget
Understanding functional genomics is critical to advance genetic research and therapeutic discovery. Dharmacon Reagents support researchers on this journey at the DNA, RNA, and protein level with the broadest range of functional genomic tools including industry leading gene modulation and gene editing solutions to help elucidate complex biological networks for functional genomic studies.
Dharmacon Reagents have you covered with a complete range of genomic solutions from single-gene experiments to whole genome screens facilitating advancements in genetic research and therapeutic discovery.
Known for almost 30 years as premier providers of synthetic oligonucleotides, Dharmacon Reagents were the first to offer algorithm designed synthetic siRNA for RNAi, and the first to offer guide RNA for CRISPR-Cas9 gene editing applications. Download our infographic to learn more about our journey of innovation.
Want to learn more? Check out our recent blog articles, read about gene editing and RNAi technologies on our application webpages, or search our knowledge base for recent videos, posters, protocols, web tools, and more.
Ready to get started? Browse our reagents here or contact our scientific support team anytime for experimental planning, support, and troubleshooting.
RNA interference
The most simple yet effective method for target gene knockdown in loss-of-function experiments
cDNA & ORF clones
Premium cDNA & ORF clones for gene overexpression studies
CRISPR gene editing
Precisely edit any gene in any cell type at any scale
CRISPR modulation
CRISPR modulation, Up- or down- regulate gene function at the transcriptional level, without cutting the DNA
Screening libraries
Select from whole genome or gene family catalog CRISPR and RNAi libraries or create a custom library in pooled or arrayed format
Custom libraries
Use our Cherry-pick library tool to turn your gene list into a custom mini-library of synthetic oligos or lentiviral reagents
Transfection reagents and buffers
Proven DharmaFECT™ transfection reagents, ancillary buffers, and media
Ready to learn more?
Our technical resources are created by our scientists and provide a vast repository of applications, troubleshooting, learning opportunities and problem resolutions. Review these resources by selecting a resource type from the list below.
30 years of Dharmacon reagent innovation
The first premier providers of synthetic RNA oligos...learn about our innovative journey
Ready to get started?
Browse our reagents from the menu on the left.
Need more help? Contact our scientific support team for experiment planning, support, and troubleshooting.
Need more help? Contact our scientific support team for experiment planning, support, and troubleshooting.