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Human siRNA Libraries

Supporting more strategies for successful screening. Find the right predefined gene family for your discovery efforts, including druggable genes or whole genome.  Libraries available in SMARTpool or individual siRNA format for ON-TARGETplus, siGENOME and Accell technologies.

Click on a collection ✔ to view availability and ordering information.

If you have a gene list of your own not reflected in these predefined collections, submit a quote request for a custom siRNA library.

  ON-TARGETplus siGENOME Accell
Cell Cycle Regulation  
Cytokine Receptors  
Deubiquitinating Enzymes
DNA Damage Response
Drug Targets
Druggable Genome    
G Protein-Coupled Receptors (GPCR)
Ion Channels
Membrane Trafficking  
Nuclear Receptor  
Protein Kinases
Serine Proteases    
Transcription Factors
Tyrosine Kinases
Ubiquitin Conjugation Subset 1  
Ubiquitin Conjugation Subset 2  
Ubiquitin Conjugation Subset 3  
Ubiquitin Enzymes
Long noncoding RNA (Lincode)

Which siRNA is right for you?

Horizon offers four complete predesigned product lines across human, mouse and rat genomes. Use the table below to help you determine the right siRNA product line for your needs.

  Cost-effective, efficient silencing High specificity for reduced off-targets + efficient silencing Highly specific knockdown of long noncoding RNA (lncRNA) Target silencing in difficult-to-transfect cells
  siGENOME siRNA ON‑TARGETplus siRNA Lincode siRNA Accell siRNA
Predesigned for human, mouse and rat protein-coding genes  
Predesigned for human and mouse long noncoding RNA (lncRNA)      
Recommended for transfectable mammalian cells in culture  
Recommended for neuronal, suspension, primary and other difficult-to-transfect cells      
Recommended transfection reagent DharmaFECT transfection reagent DharmaFECT transfection reagent DharmaFECT transfection reagent None required
Available as SMARTpool reagent
Available as four individual siRNAs
Guaranteed knockdown by SMARTpool and 3 of 4 siRNAs    
Sense strand is modified to prevent interaction with RISC and favor antisense strand uptake Selective application when thermodynamic analysis indicates it necessary for favorable antisense RISC loading
Antisense strand seed region is modified to destabilize off-target activity and enhance target specificity    
Modifications to facilitate cellular uptake without separate transfection reagents      
Stabilizing modifications to prevent nuclease-mediated degradation      
Sequence information provided with purchase