Myeloid Cancer Panel cfDNA Reference Standard
The Myeloid Cancer Panel cfDNA reference standard is a well-characterized cell line-derived control which contains 15 clinically-relevant variants across 14 genes. This cell-free DNA reference material allows labs to perform reliable and cost-effective validations of myeloid cancer liquid biopsy assays. QC pipelines are supported by controls manufactured under ISO:13485 with low allele frequencies, designed specifically to replicate cell-free patient samples in minimal residual disease (MRD) and liquid biopsy assays.
Genes covered: ABL1, ASXL1, CBL, DNMT3A, EZH2, FLT3, IDH1, IDH2, JAK2, NPM1, NRAS, SF3B1, TET2, TP53
COSMICs: 15. See table below for full details
Allelic frequencies: 0.50% - 1.00%
Buffer: Tris-EDTA (10mM Tris-HCl, 1mM EDTA), pH 8.0
Fragment size: 160 bp
Unit size: 350 ng per vial
Concentration: 20 ng/µl
|Gene||COSMIC ID (v97)||DNA sequence change||Amino acid change||Expected allelic frequency (%)|
Expiration: See all product shelf life information
Fragmentation size: D1000 DNA ScreenTape assay
Allelic frequency: Droplet Digital™ PCR
Quantification: Qubit® dsDNA BR assay (Invitrogen)
We accept orders using the following methods.
Our online catalog and ordering system can be used to search our full menu of available Reference Standards. Select your desired reference standards and add them to the shopping basket. Your order can be submitted instantly using credit card, telephone ordering or a purchase order number as the preferred payment method.
If you prefer to send us orders outside our online ordering system, please see the Contact Us page for telephone, fax, and email details in order to place an order. We recommend that you use our online system to identify the products you require and their respective “HD” product codes.
To order offline we will require the following information:
- Product code(s) of the item(s) you wish to order (e.g. "HD123")
- Your name, email address, title and organization
- Shipping address and billing address with contact names
- Purchase Order number if you have one
- Telephone number
- VAT Number (European Countries only)
If you’re having trouble ordering or finding what you’re looking for, or if you require something we don’t yet offer, please contact us.
Certificate of analysis
The Myeloid DNA Reference Standard is a well characterised, cell line derived control material manufactured under ISO 13485 that contains 22 variants across 19 genes relevant to myeloid cancer
A cell-free DNA negative control designed to complement the Myeloid Cancer Panel