Mimix™ OncoPure Colorectal Cancer, FFPE reference standard

The Mimix™ OncoPure Colorectal Cancer FFPE reference standard serves as a cancer specific quality control material, specifically designed to evaluate the comprehensive performance of molecular biology assays, including qPCR, ddPCR, Sanger sequencing, and NGS.

Product name change
As part of the continuous evolution of our portfolio, we have changed the name of our range to Mimix™ reference standards to better reflect the patient-like performance they provide.

While our product range has a new name, everything you rely on remains the same:

  • Identical formulation and performance
  • Same part numbers and SKUs
  • Existing protocols and procedures
  • Same technical specifications
  • Quality and reliability you trust

No action is required from you. Future orders, product labels, documentation, and communications will reference the new product name.

Colorectal cancer (CRC) ranks as the second deadliest cancer worldwide, responsible for over 900,000 deaths annually. This figure is expected to increase by more than 80% in the next decade.*

Our Mimix™ OncoPure Colorectal Cancer FFPE reference standard offers a highly accurate representation of patient samples. It is derived from a single CRC tumor cell line without any modifications or engineering, providing a true reflection of a patient sample. With a consistent cell line background, this control enhances the reliability of your NGS and other molecular biology-based workflows to detect CRC.

Our Mimix reference standards are produced under ISO 13485 and undergo rigorous QC testing, leveraging over 14 years of experience. This means you can trust the quality of our controls and the accuracy of your results.

Batch-specific NGS data

The OncoPure Colorectal Cancer Panel FFPE Reference Standard comes with batch-specific NGS data. You can access the VCF file here. Each batch was sequenced using Agilent's CREV4 (Clinical Research Exome) kit at a depth of 250x on Aviti platform and analyzed using the Illumina DRAGEN Somatic Pipeline for mapping, sorting, and variant calling.

 

Technical Data

Format: FFPE

Section Size: 15µm

Cell Density: 1.5 x 108 cells per block. Approx. 4.5 x 105 cells per section

Expected DNA Yield: >400 ng using Promega Maxwell RSC FFPE Plus DNA Extraction kit

Genes covered: Please refer the VCF file for mutations

Allelic Frequencies: None claimed (refer to VCF file)

 

General information

Storage: 4°C

Shipping: Ambient

Expiration: See all product shelf life information

 

Quality control

Allelic frequency: Whole Exome Sequencing

Quantification: Quantifluor®

DNA Integrity:  Agarose gel electrophoresis

Manufacturing Quality:  ISO 9001:2015 and ISO 13485:2016

*Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322/caac.21834. Epub 2024 Apr 4. PMID: 38572751.

 

For research use only. Not for use in diagnostic procedures.