miRIDIAN microRNA Hairpin Inhibitor Negative Control #1
Differentiate between specific and non-specific effects with a negative control inhibitor
Choose from two universal miRIDIAN Hairpin Inhibitor Negative Controls for experiments with miRIDIAN microRNA Hairpin Inhibitors. Negative control sequences based on C. elegans microRNAs have minimal sequence identity in human, mouse, and rat.
miRIDIAN microRNA Hairpin Inhibitor Negative Controls are ideal for optimizing conditions for relevant, well-controlled microRNA modulation experiments. Both positive and negative control molecules are provided for loss-of-function microRNA studies.
Based on cel-miR-67, mature sequence: UCACAACCUCCUAGAAAGAGUAGA(MIMAT0000039)
Cel-miR-67 confirmed to have minimal sequence identity with miRNAs in human, mouse, and rat
miRIDIAN Hairpin Inhibitor Negative Controls distinguish between miRNA-specific and non-specific effects
Figure 1. | Effects of miRIDIAN microRNA Hairpin Inhibitor Negative Controls on the function of miR-21 were assayed at 48 hours after transfection of 5 nM inhibitor or negative control in H9c2, NIH3T3, or HeLa cells using DharmaFECT Duo and a dual luciferase reporter system.