Differentiate between specific and non-specific effects with a negative control mimic
Choose from two universal miRIDIAN Mimic Negative Controls for experiments with miRIDIAN microRNA Mimics. Negative control sequences based on C. elegans microRNAs have minimal sequence identity in human, mouse, and rat.
miRIDIAN microRNA Mimic Negative Controls are ideal for optimizing conditions for relevant, well-controlled microRNA modulation experiments. Both positive and negative control molecules are provided for gain-of-function microRNA studies.
Based on cel-miR-239b, mature sequence: UUGUACUACACAAAAGUACUG(MIMAT0000295)
Cel-miR-239b confirmed to have minimal sequence identity with miRNAs in human, mouse, and rat
miRIDIAN microRNA Mimic Negative Controls have no apparent effect on tested miRNA function
Figure 1. | Effects of miRIDIAN microRNA Mimic Negative Controls on the function of three human miRNAs were assayed at 24 hours after transfection of 10 nM mimic or negative control in HeLa cells using a dual luciferase reporter system.