We have updated the ordering process to allow all products and services to be purchased with a single PO, please address all POs to Horizon Discovery Biosciences Limited. Contact us for assistance.

See the capabilities Dharmacon brings to your research

Find the ideal RNAi, gene expression and gene editing products for your applications

Horizon products enable your investigation of gene functions, biological pathway exploration, protein production, drug target identification, and so much more.

RNA Interference

The most complete portfolio of innovative tools for transient, long-term, inducible and in vivo RNAi applications.

RNAi Screening Libraries

With siRNA, shRNA, microRNA, pooled and custom libraries – we are the RNAi library experts!

Gene Expression

One of the largest collections of cDNA and ORF clones available for mammalian and non-mammalian genetic model species.

Gene Editing

Multiple strategies for guide RNAs and Cas9 nuclease expression to achieve the highest gene editing efficiencies.

Custom RNA Synthesis

Trust two decades of expertise in RNA synthesis chemistry to provide high-quality custom single-strand RNA, siRNA, and microRNA with an extensive range of modifications, synthesis scales, and purification choices.

Additional Resources

Selection guides will help you navigate to the right products for your particular applications and experimental goals.


Additional Information 

  • Applications for gene knockdown, microRNA, RNAi screening, gene expression and genome editing.
  • Find supporting resources for our products
  • Leading brands for gene knockdown, microRNA, RNAi screening, gene expression and genome editing.