Learn about methods for CRISPR activation and determine the best path for your preferred cell model and experimental parameters.
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Need to incorporate human cell models in your work but unsure where to begin? The use of iPSCs as a model system is a smart place to start.
Gene modulation is now more flexible and accessible thanks to Horizon's new CRISPRmod CRISPRi portfolio. The system leverages an inactive Cas9 complex to block transcription resulting in precision targeted gene down regulation. Read more about our newest offering:
A summary of a recent publication in The Journal of Biotechniques showing the utility of Horizon's synthetic sgRNA for CRISPR mediated transcriptional activation studies.