Gene modulation is now more flexible and accessible thanks to Horizon's new CRISPRmod CRISPRi portfolio. The system leverages an inactive Cas9 complex to block transcription resulting in precision targeted gene down regulation. Read more about our newest offering:
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A summary of a recent publication in The Journal of Biotechniques showing the utility of Horizon's synthetic sgRNA for CRISPR mediated transcriptional activation studies.
A roundtable discussion with several of the women scientists at Horizon Discovery's Boulder office sharing personal reflections after Jennifer Doudna along with Emmanuelle Charpentier won the Nobel Prize in Chemistry this year.
Examples of studies using siRNAs targeting lncRNAs to inspire your next experiment.
Are you new to RNAi experiments and need some guidance on troubleshooting?
Tips and tricks for RNAi success - make sure to include necessary controls in your transfections!
Choosing the right cell-based screen from the plethora of options available can quickly become a complicated decision process. Here, we review two of the major options: cell panel and functional genomic screening.
The only self-delivering siRNA for difficult-to-transfect cells carries a functional guarantee.
RNA sequencing (RNA-seq) of oncogenic fusions is becoming increasingly popular in cancer research and diagnosis. Here, we talk about the benefits of using RNA in fusion detection workflows, the challenge of workflow variability and how to be confident of your assay results.
Get a head start when planning your next RNA interference experiments with our most popular advice.