A complete portfolio of positive and negative experimental controls to optimize conditions and design relevant microRNA modulation experiments. Critical to any successful microRNA modulation experiment, the right controls enable accurate interpretation for reliable results. Fluorescently labeled controls are also available for visual tracking.

Choose from our collection of validated positive and negative miRIDIAN Mimic controls for use in human, mouse or rat.

miRIDIAN microRNA Mimics perform better than native double-stranded microRNA

Figure 1. | miRNA mimic function was assayed in HeLa cells 24 and 48 hours after transfection of 10 nM miR-375 native double-stranded mimic, native double-stranded mimic with modifications, or the miRIDIAN microRNA Mimic using a dual luciferase reporter system and normalized to the control (no mimic).

miRIDIAN microRNA Mimics simulate endogenous mature miRNA function

Figure 2. | miRIDIAN microRNA Mimic function for 11 human miRNAs was assayed in HeLa and HepG2 cells 48 hours after transfection of 10 nM mimic using a dual luciferase reporter system and normalized to the control (no mimic treatment). Similar results were obtained with 1 nM miRIDIAN microRNA Mimic (results not shown).