Performing RNAi with a shRNA vector is often a straightforward and well documented approach to gene knockdown.
Isolation of genomic DNA from formalin fixed paraffin embedded (FFPE) tissues is a critical step for molecular diagnostic (MDx) assays. Here we investigate extraction of DNA from FFPE using five comparable methods.
We learn of several reasons why cell line derived standards have a distinct advantage on other source materials when it comes to NGS oncology assays.
Xenopus ORF entry clone library derived from the XGC!
A look inside the University of Colorado’s RNA Club
Ready for CRISPR-Cas9 gene editing? Read on to learn about including the proper negative controls.
Discovery Horizon's CRISPRmod systems (CRISPR interference and CRISPR activation) for translational modulation of target gene expression. Learn how each system works, when to use CRISPRi for down-regulation or CRISPRa for up-regulation of endogenous gene expression, and how to design successful experiments using these reagents.
View the new poster presentation video demonstrating the creation of knockins with the EditR CRISPRC
Lipid-mediated transfection of CRISPR-Cas9 and single-strand DNA oligos for homology-directed repair
Learn the key similarities and differences in design and application
Faster alignments increase productivity!