Here we explain the hurdles to setting up a high-throughput ORF screen, and how CRISPRa offers a new solution that can expand the screening toolbox to maximize your window of discovery.
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Thinking about doing CRISPR screening for knock out, CRISPR activation or CRISPRi applications? Unsure whether a synthetic arrayed or pooled lentiviral screening library is best for your project? We are here to help.
Here we talk about the role of the Edit-R Pooled sgRNA Indexing PCR Primers and answer the most common questions about the Indexing PCR and Sequencing Primer kit.
Achieve DNA-free guaranteed gene editing with synthetic predesigned sgRNA reagents and libraries covering the entire human genome.
Did your initial round of RNAi screening produce some hits? How do you determine which hits are true positives?
Check out the BioIT Beta Tools page to test tools created by our BioIT team!
Sometimes a human promoter is optimal in mouse cells and vice versa. Dharmacon has solutions to investigate the best promoter for your cell type.
Choosing the right cell-based screen from the plethora of options available can quickly become a complicated decision process. Here, we review two of the major options: cell panel and functional genomic screening.
Functional genomic screening libraries that represent the most current findings within the field
CRISPR-Cas9 lentiviral sgRNA pooled screening changes everything.