Read about the top 4 considerations when deciding between clones and pools
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Technology from Horizon Discovery has been awarded Top Innovation of the Year by The Scientist Magazine for the past seven consecutive years.
The rapid evolution of the CRISPR-Cas9 gene editing field has led to a proliferation of technology formats and applications that can seem intimidating for the first-time researcher.
Review of selected articles showing the broad applicability of the HAP1 cell line between 2011 and 2019.
Verify proper intracellular localization from HDR experiments with an IN Cell Analyzer 2200
An innovative workflow to guide the insertion of 10-12 nucleotides into a gene of interest
HAP1 cell lines are a popular choice to validate a range of research experiments, but if you've never used them before, you want to be sure they are right for you.
After all the hard work of editing your cell line, you want to have confidence in your new research model. So, how do you verify your cell line is what you expect it to be? Could a heterogeneous cell population be obscuring your editing effects? Is observed phenotype being caused by the targeted gene edit, or unintended off-target effects? Here we discus ways to add supporting data to validate your gene-engineering projects.
CRISPR-edited cell lines are a useful tool to validate your antibodies before you start an experiment. They ensure you are using high quality reagents, so you can be confident in your results. Here we explain how you can use our edited cell lines for validation, the challenges to be aware of and how we can help you overcome them.
A major study has been undertaken to gain a better understanding of thousands of mutations in the BRCA1 gene - a key gene in breast and ovarian cancers.