dCas9-VPR mRNA for quick transcriptional activation and enrichment in any cell line While genome engineering is widely ascribed with the capacity to knock out genes of interest, new adaptations of these same molecular building-blocks are reshaping the way researchers think about the opposite: overexpression experimen August 12, 2019 5 minute read Gene editing
Gene overexpression: CRISPRa, cDNA or ORF? Which gene expression technology is best for my experiment? August 4, 2019 7 minute read Gene modulation
CRISPRa downstream effects now it gets interesting Detecting signaling effects of IL1R2 overexpression by CRISPRa with synthetic crRNAs July 26, 2019 3 minute read Gene modulation
Protect your precious pellet Resources for proper handling, resuspension and quantification of your synthetic RNA July 22, 2019 1 minute read
Publish your Gene Editing Results with a Trusted Partner Dharmacon™ Edit-R™ has been featured in over 20 peer-reviewed publications since 2015 July 22, 2019 4 minute read Gene editing
Our patented 2'-ACE chemistry enables advanced RNA synthesis Longest RNA molecules synthetically possible, with virtually any chemical modification July 22, 2019 2 minute read Custom synthesis
Optimize your transfections with the Cytell Cell Imaging System Quantitative measurement removes the guesswork from siRNA transfection optimization July 22, 2019 2 minute read Gene modulation Functional genomic screening
Mythbusting single vs two part synthetic guide RNAs Uncovering the truth about the differences between these CRISPR-Cas9 guide RNA formats July 22, 2019 4 minute read Gene editing
Multiplexed HDR knockin - Yes you can! Simultaneously insert two different fluorescent reporters July 22, 2019 2 minute read Gene editing