Sometimes dead cells are a good thing! Universal cell death controls for CRISPR-Cas9 optimization.
Want to optimize RNAi experiments in difficult-to-transfect cell lines? Read our workflow recommendations for optimal delivery and functional silencing with Accell siRNA.
Here we explain the hurdles to setting up a high-throughput ORF screen, and how CRISPRa offers a new solution that can expand the screening toolbox to maximize your window of discovery.
A discussion of novel methodology and research in primary human monocytes recently published by the labs of Dr. Alex Marson and Dr. Nevan Krogan.
Learn how to use our Dharmacon™ siDESIGN center for isoform or gene variant-specific siRNAs
Need to incorporate human cell models in your work but unsure where to begin? The use of iPSCs as a model system is a smart place to start.
Detecting proteins with confidence starts with antibody validation. Here, we've outlined the key points.
Gene modulation is now more flexible and accessible thanks to Horizon's new CRISPRmod CRISPRi portfolio. The system leverages an inactive Cas9 complex to block transcription resulting in precision targeted gene down regulation. Read more about our newest offering:
We’re happy to discuss your project in English, French, German, Italian, or Spanish; and have teams in both the US and Europe to provide flexible service hours.
Review of publications using HAP1 cells to set up validation assays beyond the typical western blot.