Ready for gene editing? Get started with our All-in-one lentiviral system, an easy to use, single reagent for CRISPRko.
A proof-of-concept study where CRISPR-Cas9 reagents and guides to 3 genes were added to the same cell population and then a representative subset of clonal cell lines were analyzed for multiplexed gene editing efficiency.
Sometimes dead cells are a good thing! Universal cell death controls for CRISPR-Cas9 optimization.
Want to optimize RNAi experiments in difficult-to-transfect cell lines? Read our workflow recommendations for optimal delivery and functional silencing with Accell siRNA.
Here we explain the hurdles to setting up a high-throughput ORF screen, and how CRISPRa offers a new solution that can expand the screening toolbox to maximize your window of discovery.
A discussion of novel methodology and research in primary human monocytes recently published by the labs of Dr. Alex Marson and Dr. Nevan Krogan.
Learn how to use our Dharmacon™ siDESIGN center for isoform or gene variant-specific siRNAs
Need to incorporate human cell models in your work but unsure where to begin? The use of iPSCs as a model system is a smart place to start.
Detecting proteins with confidence starts with antibody validation. Here, we've outlined the key points.
Gene modulation is now more flexible and accessible thanks to Horizon's new CRISPRmod CRISPRi portfolio. The system leverages an inactive Cas9 complex to block transcription resulting in precision targeted gene down regulation. Read more about our newest offering: