If you are wondering the best way to monitor the result of your gene editing experiment, we have reviewed the most commonly applied assays used.
Learn how ON-TARGETplus siRNA from Dharmacon ensures target specificity while avoiding off-target effects to give you confidence in your RNAi studies.
Ready for gene editing? Get started with our All-in-one lentiviral system, an easy to use, single reagent for CRISPRko.
A proof-of-concept study where CRISPR-Cas9 reagents and guides to 3 genes were added to the same cell population and then a representative subset of clonal cell lines were analyzed for multiplexed gene editing efficiency.
Sometimes dead cells are a good thing! Universal cell death controls for CRISPR-Cas9 optimization.
Want to optimize RNAi experiments in difficult-to-transfect cell lines? Read our workflow recommendations for optimal delivery and functional silencing with Accell siRNA.
Here we explain the hurdles to setting up a high-throughput ORF screen, and how CRISPRa offers a new solution that can expand the screening toolbox to maximize your window of discovery.
A discussion of novel methodology and research in primary human monocytes recently published by the labs of Dr. Alex Marson and Dr. Nevan Krogan.
Learn how to use our Dharmacon™ siDESIGN center for isoform or gene variant-specific siRNAs
Need to incorporate human cell models in your work but unsure where to begin? The use of iPSCs as a model system is a smart place to start.