Learn about the MLR assay and why it is an essential component of the compound screening pipeline for drug development.
Describes methods of testing your cell culture for retroviral recombination.
CRISPR gene editing and siRNA gene silencing require the efficient delivery of the necessary reagents. This is easily achieved by optimizing delivery conditions. In this blog post we discuss techniques for optimization of a reverse transfection conditions and how to set up a 96 well plate to test 30 transfection conditions.
Learn how to examine your NGS data to investigate false positives and negatives, and potential downstream applications
Learn how to use Dharmacon™ Edit-R™ CRISPR reagents to make functional knockout models in human iPSCs.
Discover Pin-point™, a first-generation base editing technology that we have licensed from Rutgers, a system we’ve since developed further to accelerate therapeutic development. Read the popular article now and see more of our recent advancements in the base editing space.
New advances in the use of base editing technology for treating sickle cell disease highlight the therapeutic promise of base editing in cell and gene therapy.
Accell siRNA has been widely literature-cited for gene silencing in primary immune cells, which have historically been difficult to transfect. Learn more here.
The CRISPR Design Tool enables targeting any region of a genome, even in non-standard species
Guidelines for making the most out of your CRISPR experiment