Single-cell CRISPR screens
- Perform high-throughput screens
- Generate ultra-rich whole-transcriptome readouts per perturbation
- Distinguish cell subpopulation gene responses to perturbation
CRISPR screening followed by single-cell analysis (CRISPRsc) provides critical gene information on how cellular subpopulations will respond to any treatment.
CRISPRsc enables an unbiased examination of critical genes involved in a phenotypic outcome within a heterogenous cell population, such as a tumor or group of cells at different temporal points in a pathway. This supports greater understanding of differences in cellular responses and subpopulation structure.
Use single-cell CRISPR screens to:
- Study variation in cellular differentiation pathways
- Characterize cell subpopulations
- Clearly identify gene interactions and networks
- Understand differences in cell responses to a treatment
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CRISPRsc identifies pathways affecting treatment response
CRISPRsc provides a new and powerful approach to quickly identify the genetic interactions that underlie a treatment response. Read our application note to learn more.
'On the Horizon' blog
Read our blog to learn more about CRISPRsc and other Horizon news.