Cell panel screening services

From drug discovery to patient stratification.
Screen in 2D and 3D models - spheroids or organoids.

Standard drug screening service - 2D OncoSignature™

Identify cells that respond to your therapeutics:

  • Select from a bank of 300 standard cancer cell lines or send us your cell lines
  • Single agent or combination screening
  • Receive report in 4 months
  • Expert bioinformatics analysis available as an 'optional add-in' to look for markers of response

Standard drug screening service - 3D OncoSignature™

Predict which patient populations might be most responsive to a drug or biologic.

Analyze your candidate therapeutics:

  • Test in spheroids to better mimic tumor micro-environment
  • Select from a bank of 200 standard cancer cell lines from a variety of backgrounds
  • Single agent or combination screening
  • Expert bioinformatics analysis available as an 'optional add-in' to look for markers of response

Custom screening services

Create your own screen specifications. Benefit from combination therapeutic screens, complex or different disease type cells.

Consult with your dedicated project team to define project scope:

  • Select standard or genetically modified cancer cell lines or send us your cell lines
  • Choose from a range of end-point assays
  • Opt for OncoReference data set to aid with cell line selection

Immune cell-based assays

Understand MOA, test biosimilars or identify biomarkers:

  • Evaluate in primary B cells, T cells, NK cells, MoDC, MDSC or macrophage-based assays
  • Select from a range of multiplexed assay readouts
  • Compatible with CRISPR & RNAi screens

Poster: Screening using organoids

Read about the benefits of using 3D systems to mimic tumor microenvironments in our AACR 2019 poster - 

'High-Throughput Cell Panel and Organoid Screening in 3D.'

OncoReference

Benchmark your compound activity against 200 single agent compounds screened over a panel of 150 cancer cell lines from 19 different indications. Including standard-of-care, emerging therapeutics, and targeted probes

  • Identify the mechanism of action (MoA) of your test compound
  • Identify the patient population to test your compound
  • Identify potential drug combination partners
  • Benchmark your compound against the current standard of care drugs

Video: Combination screens

Drug combination screens

Brochure: Cell Panel Screening Services

Learn more about our OncoSignature™ and custom cell panel services.

Helping you from target validation to phase 1 trials.

Want to discuss a project idea?

From consultation to delivery. We're always here to help.