Standard cell panel screen - 2D OncoSignature™

Identify sensitive and resistant cell lines
  • Pre-selected cancer cell lines (Horizon's library)
  • Single therapeutic drug screening or combination drug screening
  • Growth inhibition measure by ATP levels

Long-term cell panel screen – 2D OncoSignature™

Identify slow acting and epigenetic targets
  • 10-days assay format
  • Large panel of 248 cancer cell lines
  • Single or combination studies
  • Growth inhibition measured by ATP levels

Matrix combination screens

Find out the benefits of drug combination screening and how it helps improve cancer therapies.

The importance of combination therapy for modern cancer treatments

Combination drug therapy is fundamental in cancer treatments for increased efficacy and reducing resistance. Read this whitepaper on how using a high-throughput, phenotypic combination screen can help make informed decisions to select the most promising candidate

The impact of pan-KRAS inhibitors on cancer drug discovery

'We included data generated by Horizon as part of this Nature publication because they have consistently provided high quality, actionable data that we trust, and we look forward to continuing our work with them.'

Read a review of the paper showing how cell panel screening was used to shed light on the development of a new class of Pan-KRAS inhibitors and their potential impact on cancer drug discovery

Reveal the anti-proliferative signature of your drug

Use Horizon's screening services to identify sensitive or resistant cell lines to your drug 

'Horizon's OncoSignature HT screening platform for the prediction of anticancer drug sensitivity'

Book a consultation with our screening experts

We're here to support informed decision making by providing:

  • Collaborative approach
  • Dedicated project manager
  • Regular updates & interim data
  • Detailed study report including raw data files and a free copy of our analysis workbench software

App note: Compound screening in BRCA2 (-/-) cell lines

Isogenic cells are a powerful and relevant tool for therapeutic discovery and development.

View our results from:

  • Colony forming assay
  • Proliferation assay